CHSY1 antibody

Catalog No. ABIN7112731

This Rabbit Polyclonal antibody specifically detects CHSY1 in WB, ELISA and IHC. It exhibits reactivity toward Human, Mouse, Rat and Zebrafish (Danio rerio).

Quick Overview for CHSY1 antibody (ABIN7112731)

Target: CHSY1 (Chondroitin Sulfate Synthase 1 (CHSY1))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHSY1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-CHSY1 Antibody

Purpose: CHSY1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: chondroitin sulfate synthase 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for CHSY1

Target: CHSY1 (Chondroitin Sulfate Synthase 1 (CHSY1))

Alternative Name: CHSY1

Background:

Synonyms: Chondroitin sulfate synthase 1|Chondroitin glucuronyltransferase 1|Chondroitin synthase 1 (ChSy-1)|Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1|N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1|N-acetylgalactosaminyltransferase 1|CHSY1|CHSY|CSS1|KIAA0990

Background: Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid(GlcUA) from UDP-GlcUA and N-acetylgalactosamine(GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling.

Molecular Weight: 66 kDa

Gene ID: 22856

UniProt: Q86X52

Pathways: Glycosaminoglycan Metabolic Process