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CEP290 antibody

CEP290 Reactivity: Human, Mouse, Rat ELISA, WB, IHC, IF, IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7112607
  • Target See all CEP290 Antibodies
    CEP290 (Centrosomal Protein 290kDa (CEP290))
    Reactivity
    • 28
    • 24
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 41
    • 2
    Rabbit
    Clonality
    • 43
    Polyclonal
    Conjugate
    • 19
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CEP290 antibody is un-conjugated
    Application
    • 15
    • 14
    • 13
    • 13
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    Purification
    Immunogen affinity purified
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    centrosomal protein 290kDa
    Isotype
    IgG
    Top Product
    Discover our top product CEP290 Primary Antibody
  • Application Notes
    WB: 1:200-1:2000, IP: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:50-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    CEP290 (Centrosomal Protein 290kDa (CEP290))
    Alternative Name
    CEP290 (CEP290 Products)
    Synonyms
    ct87 antibody, mks4 antibody, rd16 antibody, bbs14 antibody, jbts5 antibody, jbts6 antibody, lca10 antibody, nphp6 antibody, slsn6 antibody, sh11ag antibody, MGC81471 antibody, 3h11ag antibody, RGD1311640 antibody, BC004690 antibody, Nphp6 antibody, b2b1454Clo antibody, b2b1752Clo antibody, im:7145703 antibody, im:7147820 antibody, 3H11Ag antibody, BBS14 antibody, CT87 antibody, JBTS5 antibody, LCA10 antibody, MKS4 antibody, NPHP6 antibody, POC3 antibody, SLSN6 antibody, centrosomal protein 290 antibody, centrosomal protein 290 L homeolog antibody, centrosomal protein 290kDa antibody, CEP290 antibody, cep290.L antibody, cep290 antibody, Cep290 antibody
    Background
    Synonyms:BBS14, KIAA0373, NPHP6,LCA10, MKS4, Nephrocystin 6, rd16, SLSN6, Tumor antigen se2 2 Background:Studies in the Chlamydomonas model system has shown that the ciliary protein CEP290 is a critical component of these Y-link junctions. Additionally, numerous studies have demonstrated that CEP290's function is critical for IFT-in CEP290 knockdown experiments, many proteins that would normally localize to the cilium fail to do so, and cilium formation is disrupted or absent. Mutations in CEP290 are accountable for cases of nephronophthisis, Leber congenital amaurosis and Joubert syndrome. In IF analtsis of HeLa cells, the white arrows show centrosome and cilium staining.
    Molecular Weight
    290 kDa, 150-180 kDa, 80 kDa, 60 kDa
    Gene ID
    80184
    UniProt
    O15078
    Pathways
    cAMP Metabolic Process, M Phase
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