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CEP290 antibody
CEP290
Reactivity: Human, Mouse, Rat
ELISA, WB, IHC, IF, IP
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CEP290 Antibody
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Target
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CEP290
(Centrosomal Protein 290kDa (CEP290))
Reactivity
All reactivities for CEP290 antibodies
Human, Mouse, Rat
Host
All hosts for CEP290 antibodies
Rabbit
Clonality
All clonalities for CEP290 antibodies
Polyclonal
Conjugate
All conjugates for CEP290 antibodies
This CEP290 antibody is un-conjugated
Application
All applications for CEP290 antibodies
ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
Purification
Immunogen affinity purified
Purity
≥95 % as determined by SDS-PAGE
Immunogen
centrosomal protein 290kDa
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
WB: 1:200-1:2000, IP: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:50-1:500
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Expiry Date
12 months
Target Details for CEP290
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Target
CEP290
(Centrosomal Protein 290kDa (CEP290))
Alternative Name
CEP290 (CEP290 Products )
Synonyms
ct87 antibody, mks4 antibody, rd16 antibody, bbs14 antibody, jbts5 antibody, jbts6 antibody, lca10 antibody, nphp6 antibody, slsn6 antibody, sh11ag antibody, MGC81471 antibody, 3h11ag antibody, RGD1311640 antibody, BC004690 antibody, Nphp6 antibody, b2b1454Clo antibody, b2b1752Clo antibody, im:7145703 antibody, im:7147820 antibody, 3H11Ag antibody, BBS14 antibody, CT87 antibody, JBTS5 antibody, LCA10 antibody, MKS4 antibody, NPHP6 antibody, POC3 antibody, SLSN6 antibody, centrosomal protein 290 antibody, centrosomal protein 290 L homeolog antibody, centrosomal protein 290kDa antibody, CEP290 antibody, cep290.L antibody, cep290 antibody, Cep290 antibody
Background
Synonyms:BBS14, KIAA0373, NPHP6,LCA10, MKS4, Nephrocystin 6, rd16, SLSN6, Tumor antigen se2 2 Background:Studies in the Chlamydomonas model system has shown that the ciliary protein CEP290 is a critical component of these Y-link junctions. Additionally, numerous studies have demonstrated that CEP290's function is critical for IFT-in CEP290 knockdown experiments, many proteins that would normally localize to the cilium fail to do so, and cilium formation is disrupted or absent. Mutations in CEP290 are accountable for cases of nephronophthisis, Leber congenital amaurosis and Joubert syndrome. In IF analtsis of HeLa cells, the white arrows show centrosome and cilium staining.
Molecular Weight
290 kDa, 150-180 kDa, 80 kDa, 60 kDa
Gene ID
80184
UniProt
O15078
Pathways
cAMP Metabolic Process , M Phase
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