CENPN antibody

Catalog No. ABIN7112598

This anti-CENPN antibody is a Rabbit Polyclonal antibody detecting CENPN in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for CENPN antibody (ABIN7112598)

Target: CENPN (Centromere Protein N (CENPN))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CENPN antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CENPN Antibody

Purpose: CENPN antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: centromere protein N

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for CENPN

Target: CENPN (Centromere Protein N (CENPN))

Alternative Name: CENPN

Background:

Synonyms: Centromere protein N (CENP-N)|Interphase centromere complex protein 32|CENPN|C16orf60|ICEN32

Background: Component of the CENPA-NAC(nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD(nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPN is the first protein to bind specifically to CENPA nucleosomes and the direct binding of CENPA nucleosomes by CENPN is required for centromere assembly. Required for chromosome congression and efficiently align the chromosomes on a metaphase plate.

Molecular Weight: 40 kDa, 25-30 kDa

Gene ID: 55839

UniProt: Q96H22