CD320 antibody

Catalog No. ABIN7112479

Product Details anti-CD320 Antibody

Target: CD320 (CD320 Molecule (CD320))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD320 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: CD320 molecule

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for CD320

Target: CD320 (CD320 Molecule (CD320))

Alternative Name: CD320 (CD320 Products)

Synonyms: 8D6 antibody, 8D6A antibody, TCBLR antibody, 425O18-1 antibody, D17Ertd716e antibody, NG29 antibody, VLDL antibody, RGD1305860 antibody, TCblR antibody, CD320 molecule antibody, CD320 antigen antibody, CD320 antibody, Cd320 antibody

Background: Synonyms:8D6, 8D6 antigen, 8D6A, CD320, CD320 antigen, CD320 Molecule, FDC signaling molecule 8D6, FDC SM 8D6, TCblR, Transcobalamin receptor Background:CD320, also known as 8D6, 8D6A or TCblR, is a single-pass type I membrane protein containing 2 LDL-receptor class A domains. Expressed abundantly on follicular dendritic cells (FDCs), CD320 has been shown to enhance proliferation of germinal center (GC) B cells. It is the receptor for cellular uptake of transcobalamin-bound cobalamin. Defects in CD320 are the cause of methylmalonic aciduria type TCblR (MMATC). CD320 has a calculated molecular mass of 29 kDa. This antibody detects bands at 50-55 kDa and 60-70 kDa, probably caused by extensive complex glycosylation.

Molecular Weight: 50-55 kDa, 60-70 kDa

Gene ID: 51293

UniProt: Q9NPF0