Alanine--tRNA Ligase, Mitochondrial (AARS-1) antibody
Quick Overview for Alanine--tRNA Ligase, Mitochondrial (AARS-1) antibody (ABIN7111429)
Target
Reactivity
Host
Clonality
Conjugate
Application
-
-
Purpose
- AARS1 antibody
-
Purification
- Immunogen affinity purified
-
Purity
- ≥95 % as determined by SDS-PAGE
-
Immunogen
- alanyl-tRNA synthetase
-
Isotype
- IgG
-
-
-
-
Application Notes
- WB: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handling Advice
- Avoid repeated freeze / thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- -20°C for 12 months
-
Expiry Date
- 12 months
-
-
- Alanine--tRNA Ligase, Mitochondrial (AARS-1)
-
Alternative Name
- AARS1
-
Background
-
Synonyms: Alanine--tRNA ligase, cytoplasmic|Alanyl-tRNA synthetase (AlaRS)|Renal carcinoma antigen NY-REN-42|AARS1|AARS
Background: AARS(alanyl-tRNA synthetase) is also named as AlaRS(alanine tRNA ligase 1, cytoplasmic), renal carcinoma antigen NY-REN-42 and belongs to the class-II aminoacyl-tRNA synthetase family. It can interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. AARS consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs(PMID:19661429).
-
Molecular Weight
- 107 kDa
-
Gene ID
- 16
-
UniProt
- P49588
Target
-
