ARL2 antibody

Catalog No. ABIN7111380

Product Details anti-ARL2 Antibody

Target: ARL2 (ADP-Ribosylation Factor-Like 2 (ARL2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: ADP-ribosylation factor-like 2

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for ARL2

Target: ARL2 (ADP-Ribosylation Factor-Like 2 (ARL2))

Alternative Name: ARL2 (ARL2 Products)

Synonyms: arfl2 antibody, MGC75676 antibody, ARFL2 antibody, 2610009M23Rik antibody, AI115441 antibody, AW553335 antibody, ADP ribosylation factor like GTPase 2 antibody, ADP-ribosylation factor-like 2 antibody, ADP-ribosylation factor like GTPase 2 antibody, arl2 antibody, ARL2 antibody, Arl2 antibody

Background: Synonyms: Background:Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors(GEF) and GTPase-activating proteins(GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassembly of the apical junction complexes. Antagonizes the effect of TBCD on epithelial cell detachment and tight and adherens junctions disassembly. Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. Component of a regulated secretory pathway involved in Ca(2+)-dependent release of acetylcholine. Required for normal progress through the cell cycle.

Molecular Weight: 21-25 kDa

Gene ID: 402

UniProt: P36404

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location