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ARL2 antibody

ARL2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7111380
  • Target See all ARL2 Antibodies
    ARL2 (ADP-Ribosylation Factor-Like 2 (ARL2))
    Reactivity
    Human, Mouse, Rat
    Host
    • 46
    • 1
    • 1
    Rabbit
    Clonality
    • 48
    Polyclonal
    Conjugate
    • 18
    • 6
    • 5
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARL2 antibody is un-conjugated
    Application
    • 32
    • 26
    • 14
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    Immunogen affinity purified
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    ADP-ribosylation factor-like 2
    Isotype
    IgG
    Top Product
    Discover our top product ARL2 Primary Antibody
  • Application Notes
    WB: 1:500-1:2000, IHC: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    ARL2 (ADP-Ribosylation Factor-Like 2 (ARL2))
    Alternative Name
    ARL2 (ARL2 Products)
    Synonyms
    arfl2 antibody, MGC75676 antibody, ARFL2 antibody, 2610009M23Rik antibody, AI115441 antibody, AW553335 antibody, ADP ribosylation factor like GTPase 2 antibody, ADP-ribosylation factor-like 2 antibody, ADP-ribosylation factor like GTPase 2 antibody, arl2 antibody, ARL2 antibody, Arl2 antibody
    Background
    Synonyms: Background:Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors(GEF) and GTPase-activating proteins(GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassembly of the apical junction complexes. Antagonizes the effect of TBCD on epithelial cell detachment and tight and adherens junctions disassembly. Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. Component of a regulated secretory pathway involved in Ca(2+)-dependent release of acetylcholine. Required for normal progress through the cell cycle.
    Molecular Weight
    21-25 kDa
    Gene ID
    402
    UniProt
    P36404
    Pathways
    Cell-Cell Junction Organization, Maintenance of Protein Location
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