ARL13B antibody

Catalog No. ABIN7111377

This anti-ARL13B antibody is a Rabbit Polyclonal antibody detecting ARL13B in WB, IF, ELISA, IHC and IP. Suitable for Human, Mouse, Rat and Dog.

Quick Overview for ARL13B antibody (ABIN7111377)

Target: ARL13B (ADP-Ribosylation Factor-Like 13B (ARL13B))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARL13B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-ARL13B Antibody

Purpose: ARL13B antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: ADP-ribosylation factor-like 13B

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:500-1:2000, IHC: 1:50-1:500, IF: 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ARL13B

Target: ARL13B (ADP-Ribosylation Factor-Like 13B (ARL13B))

Alternative Name: ARL13B

Background:

Synonyms: ADP-ribosylation factor-like protein 13B|ADP-ribosylation factor-like protein 2-like 1 (ARL2-like protein 1)|ARL13B|ARL2L1

Background: Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it, the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic interneurons in the developing cerebral cortex. May regulate endocytic recycling traffic, however, additional evidences are required to confirm these data.

Molecular Weight: 40-48 kDa, 66 kDa

Gene ID: 200894

UniProt: Q3SXY8