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Adenylosuccinate Lyase antibody

ADSL Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, FACS Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7111349
  • Target See all Adenylosuccinate Lyase (ADSL) Antibodies
    Adenylosuccinate Lyase (ADSL)
    Reactivity
    • 44
    • 20
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 40
    • 4
    Rabbit
    Clonality
    • 41
    • 2
    Polyclonal
    Conjugate
    • 19
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Adenylosuccinate Lyase antibody is un-conjugated
    Application
    • 16
    • 13
    • 13
    • 9
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
    Purification
    Immunogen affinity purified
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    adenylosuccinate lyase
    Isotype
    IgG
    Top Product
    Discover our top product ADSL Primary Antibody
  • Application Notes
    WB: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:10-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    Adenylosuccinate Lyase (ADSL)
    Alternative Name
    Adenylosuccinate lyase (ADSL Products)
    Synonyms
    fi60b04 antibody, zgc:56061 antibody, wu:fi60b04 antibody, MGC53383 antibody, MGC69239 antibody, adsL antibody, F15C21.8 antibody, F15C21_8 antibody, AMPS antibody, ASASE antibody, ASL antibody, Adl antibody, Asl antibody, purB antibody, adenylosuccinate lyase antibody, adenylosuccinate lyase L homeolog antibody, adenylosuccinase; ASL antibody, Adenylosuccinate lyase antibody, L-Aspartase-like family protein antibody, ADSL antibody, adsl antibody, adsl.L antibody, ASL antibody, purB antibody, purB,adsL antibody, Mrub_2293 antibody, MMAH_RS02975 antibody, Arnit_0089 antibody, Mesil_1058 antibody, Slip_0597 antibody, Trad_2452 antibody, Deba_0652 antibody, Toce_1174 antibody, Acear_2324 antibody, Igag_0272 antibody, Saut_2156 antibody, Fbal_1996 antibody, Ndas_2434 antibody, Ilyop_0196 antibody, Lbys_2961 antibody, MFER_RS02920 antibody, Palpr_2192 antibody, Calni_0061 antibody, Ftrac_3746 antibody, AT1G36280 antibody, Olsu_1764 antibody, Adsl antibody
    Background
    Synonyms:Adenylosuccinase, adenylosuccinate lyase, ADSL, AMPS, ASASE, ASL Background:ADSL(adenylosuccinate lyase) is also named as AMPS, ASase, ASL and belongs to the lyase 1 family. It is an enzyme involved in 2 pathways of purine nucleotide metabolism and catalyzes cleavage of succinyl groups to yield fumarate(PMID:18524658). Defects in ADSL are the cause of adenylosuccinase deficiency(ADSL deficiency). In humans, mutations in ADSL lead to an inborn error of metabolism originally characterized by developmental delay, often with autistic features(PMID:20884265)..The ADSL enzymatic activity is reduced in lymphocytes and red blood cells of the patient with severe psychomotor retardation(PMID:9545543). It has 2 isoforms produced by alternative splicing.
    Molecular Weight
    55 kDa
    Gene ID
    158
    UniProt
    P30566
    Pathways
    Ribonucleoside Biosynthetic Process
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