ASCC3 antibody

Catalog No. ABIN7111240

Product Details anti-ASCC3 Antibody

Target: ASCC3 (Activating Signal Cointegrator 1 Complex Subunit 3 (ASCC3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASCC3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: activating signal cointegrator 1 complex subunit 3

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for ASCC3

Target: ASCC3 (Activating Signal Cointegrator 1 Complex Subunit 3 (ASCC3))

Alternative Name: ASCC3 (ASCC3 Products)

Background: Synonyms:ASC 1 complex subunit p200, ASC1p200, ASCC3, HELIC1, Helicase, ATP binding 1, RNAH, Trip4 complex subunit p200 Background:3'-5' DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3, enabling ALKBH3 to process alkylated N3-methylcytosine(3mC) within double-stranded regions. Enhances NF-kappa-B, SRF and AP1 transactivation.

Molecular Weight: 251 kDa

Gene ID: 10973

UniProt: Q8N3C0