CXCL13 antibody (AA 23-109)

Catalog No. ABIN706691

Product Details anti-CXCL13 Antibody

Target: CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))

Binding Specificity: AA 23-109

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCL13 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse CXCL13/BCA1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-CXCL13 antibody (ABIN706691)

Doloff, Veiseh, Vegas, Tam, Farah, Ma, Li, Bader, Chiu, Sadraei, Aresta-Dasilva, Griffin, Jhunjhunwala, Webber, Siebert, Tang, Chen, Langan, Dholokia, Thakrar, Qi, Oberholzer, Greiner, Langer et al.: "Colony stimulating factor-1 receptor is a central component of the foreign body response to biomaterial implants in rodents and non-human primates. ..." in: Nature materials, Vol. 16, Issue 6, pp. 671-680, (2017) (PubMed).

Wang, Cao, Li, Zhang: "Chemokine CXCL13 expression was up-regulated in Clostridium difficile infection." in: Cytokine, Vol. 88, pp. 232-240, (2016) (PubMed).

Siepert, Brösel, Vogt, Ahrlich, Schmitt-Knosalla, Loddenkemper, Kühl, Baumgrass, Gerstmayer, Tomiuk, Tiedge, Viklický, Brabcova, Nizze, Lehmann, Volk, Sawitzki: "Mechanisms and Rescue Strategies of Calcineurin Inhibitor Mediated Tolerance Abrogation Induced by Anti-CD4 mAb Treatment." in: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, (2013) (PubMed).

Target Details for CXCL13

Target: CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))

Alternative Name: CXCL13/BCA1 (CXCL13 Products)

Synonyms: 4631412M08Rik antibody, ANGIE2 antibody, Angie antibody, BCA-1 antibody, BLC antibody, BLR1L antibody, Scyb13 antibody, ANGIE antibody, BCA1 antibody, SCYB13 antibody, C-X-C motif chemokine ligand 13 antibody, chemokine (C-X-C motif) ligand 13 antibody, Cxcl13 antibody, CXCL13 antibody

Background:

Synonyms: BLC, Angie, BCA-1, BLR1L, ANGIE2, Scyb13, 4631412M8Rik, C-X-C motif chemokine 13, B lymphocyte chemoattractant, CXC chemokine BLC, Small-inducible cytokine B13, Cxcl13

Background: Strongly chemotactic for B-lymphocytes, weakly for spleen monocytes and macrophages but no chemotactic activity for granulocytes. Binds to BLR1/CXCR5. May play a role in directing the migration of B-lymphocytes to follicles in secondary lymphoid organs.

Gene ID: 55985

UniProt: O55038