MICB antibody (AA 23-309)

Catalog No. ABIN7092967

Product Details anti-MICB Antibody

Target: MICB (MHC Class I Polypeptide-Related Sequence B (MICB))

Binding Specificity: AA 23-309

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MICB antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Purification: Powder

Immunogen: Recombinant human MICB(Ala23-Asp309) (ABIN6964108) produced by using human HEK293 cells

Clone: DM168

Isotype: IgG

Application Details

Application Notes: ELISA 1/5000-10000,Flow Cyt 1/100

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.,0.1 % Procline 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details for MICB

Target: MICB (MHC Class I Polypeptide-Related Sequence B (MICB))

Alternative Name: MICB (MICB Products)

Synonyms: PERB11.2 antibody, MHC class I polypeptide-related sequence B antibody, MHC class I-related protein-like antibody, MICB antibody, LOC512825 antibody

Background: Synonyms:MIC-B, PERB11.2
Description:This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules, however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.

Molecular Weight: 42.6KDa

Pathways: Human Leukocyte Antigen (HLA) in Adaptive Immune Response