VTA1 antibody (AA 221-306) (Biotin)

Catalog No. ABIN7091818

Product Details anti-VTA1 Antibody (Biotin)

Target: VTA1 (Vps20-Associated 1 Homolog (VTA1))

Binding Specificity: AA 221-306

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VTA1 antibody is conjugated to Biotin

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Cow,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LIP5

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for VTA1

Target: VTA1 (Vps20-Associated 1 Homolog (VTA1))

Alternative Name: LIP5 (VTA1 Products)

Synonyms: C6orf55 antibody, DRG-1 antibody, DRG1 antibody, LIP5 antibody, My012 antibody, SBP1 antibody, 1110001D18Rik antibody, 1110059P08Rik antibody, AU040813 antibody, C85340 antibody, Lip5 antibody, RGD1305031 antibody, Vps20-associated 1 homolog antibody, vesicle trafficking 1 antibody, vesicle (multivesicular body) trafficking 1 antibody, Vta1 antibody, VTA1 antibody

Background:

Synonyms: C6orf55 Chromosome 6 open reading frame 55, Dopamine responsive protein DRG 1, Dopamine-responsive gene 1 protein, DRG 1, DRG-1, DRG1, Homolog of mouse SKD1 binding protein 1, HSPC228, LIP5, LYST interacting protein 5, LYST-interacting protein 5, My012, SBP1, SKD1 binding protein 1, SKD1-binding protein 1, Vacuolar protein sorting-associated protein VTA1 homolog, Vps20 associated 1 homolog (S. cerevisiae), VTA1, VTA1_HUMAN

Background: Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR. Involved in HIV-1 budding.

Gene ID: 51534

UniProt: Q9NP79