PRDM16 antibody (AA 779-996)

Catalog No. ABIN7091539

Product Details anti-PRDM16 Antibody

Target: PRDM16 (PR Domain Containing 16 (PRDM16))

Binding Specificity: AA 779-996

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PRDM16 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: Human

Immunogen: Recombinant human PRDM16 between 779-996 amino acids.

Clone: G10T8

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for PRDM16

Target: PRDM16 (PR Domain Containing 16 (PRDM16))

Alternative Name: PRDM16 (PRDM16 Products)

Background:

Synonyms: KIAA1675, MDS1/EVI1 like gene 1, MDS1/EVI1-like gene 1, MEL1, PFM 13, PFM13, PR domain containing 16, PR domain containing protein 16, PR domain zinc finger protein 16, PR domain-containing protein 16, PRD16_HUMAN, Transcription factor MEL 1, Transcription factor MEL1.

Background: Binds DNA and functions as a transcriptional regulator. Functions in the differentiation of brown adipose tissue (BAT) which is specialized in dissipating chemical energy in the form of heat in response to cold or excess feeding while white adipose tissue (WAT) is specialized in the storage of excess energy and the control of systemic metabolism. Together with CEBPB, regulates the differentiation of myoblastic precursors into brown adipose cells. Functions also as a repressor of TGF-beta signaling. Isoform 4 may regulate granulocytes differentiation.

Gene ID: 63976

UniProt: Q9HAZ2

Pathways: Stem Cell Maintenance, Brown Fat Cell Differentiation