PKD2 antibody (AA 41-140)
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- Target See all PKD2 Antibodies
- PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))
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Binding Specificity
- AA 41-140
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PKD2 antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB)
- Cross-Reactivity
- Human
- Predicted Reactivity
- Mouse,Rat,Cow,Pig,Horse,Rabbit,Zebrafish
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Polycystin 2
- Isotype
- IgG
- Top Product
- Discover our top product PKD2 Primary Antibody
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anti-Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2) (AA 261-360) antibody
PKD2 Reactivity: Human ELISA, WB, IF Host: Mouse Monoclonal 4C8 unconjugated
anti-Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2) (AA 680-968) antibodyPKD2 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2) (pSer876) antibodyPKD2 Reactivity: Human, Mouse, Rat ELISA, WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2) (AA 937-968), (C-Term) antibodyPKD2 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB1352 unconjugated
anti-Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2) (AA 261-360) antibodyPKD2 Reactivity: Human ELISA, WB Host: Mouse Monoclonal 1G3 unconjugated
anti-Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2) (AA 240-410) antibodyPKD2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2) (AA 651-750) antibodyPKD2 Reactivity: Human, Mouse ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2) (Tyr654) antibodyPKD2 Reactivity: Human, Mouse, Rat ELISA, WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2) (C-Term) antibodyPKD2 Reactivity: Human ELISA, WB Host: Rabbit Polyclonal unconjugated
anti-Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2) (Internal Region) antibodyVerified PKD2 Reactivity: Human ELISA, WB Host: Goat Polyclonal unconjugated
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000 - Restrictions
- For Research Use only
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- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))
- Alternative Name
- Polycystin 2 (PKD2 Products)
- Background
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Synonyms: polycystic kidney disease 2, TRPP2, APKD2, C030034P18RIK, MGC138466, MGC138468, PC2, PKD2 (includes EG:5311), PKD4, POLYCISTIN-2, POLYCYSTIN 2, RGD1559992, TRPP2, Polycystic kidney disease 2 protein homolog, PC2.
Background: Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis. Acts as a regulator of cilium length, together with PKD1. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling. Functions as a calcium permeable cation channel.
- Gene ID
- 5311
- UniProt
- Q13563
- Pathways
- cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity
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