IL23R antibody (AA 231-330)
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- Target See all IL23R Antibodies
- IL23R (Interleukin 23 Receptor (IL23R))
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Binding Specificity
- AA 231-330
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IL23R antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Human
- Predicted Reactivity
- Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human IL-23R
- Isotype
- IgG
- Top Product
- Discover our top product IL23R Primary Antibody
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- Application Notes
- WB 1:300-5000
- Restrictions
- For Research Use only
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- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- IL23R (Interleukin 23 Receptor (IL23R))
- Alternative Name
- IL-23R (IL23R Products)
- Synonyms
- IL-23R antibody, IL23R antibody, il-23r antibody, interleukin 23 receptor antibody, IL23R antibody, il23r antibody, Il23r antibody
- Background
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Synonyms: IL23 Receptor, IL-23R, IL23R, interleukin 23 receptor, IL 23R, IL-23 receptor, IL23R_HUMAN, Interleukin-23 receptor.
Background: Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. Subunit : Heterodimer with IL12RB1. In presence of IL23, the heterodimer forms the IL23 receptor. Interacts with JAK2 and in presence of IL23 with STAT3.
- Gene ID
- 149233
- UniProt
- Q5VWK5
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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