Importin 9 antibody (AA 1-388)

Catalog No. ABIN7091241

Product Details anti-Importin 9 Antibody

Target: Importin 9 (IPO9)

Binding Specificity: AA 1-388

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Importin 9 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Human

Immunogen: Recombinant human RANBP9 between 1-388 amino acids.

Clone: B5F6

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Importin 9

Target: Importin 9 (IPO9)

Alternative Name: RANBP9 (IPO9 Products)

Synonyms: Imp9 antibody, 0710008K06Rik antibody, AI845704 antibody, C78347 antibody, Ranbp9 antibody, mKIAA1192 antibody, zgc:66429 antibody, wu:fc23d12 antibody, MGC81741 antibody, IPO9 antibody, DDBDRAFT_0205722 antibody, DDBDRAFT_0229883 antibody, DDB_0205722 antibody, DDB_0229883 antibody, RGD1561940 antibody, RanBPM antibody, RanBP9 antibody, bpm-l antibody, bpm90 antibody, ranbp9 antibody, ranbp9-a antibody, ranbp9-b antibody, ranbp9b antibody, cb457 antibody, zgc:158650 antibody, importin 9 antibody, importin 9 L homeolog antibody, RAN binding protein 9 antibody, RAN binding protein 9 L homeolog antibody, IPO9 antibody, Ipo9 antibody, ipo9 antibody, ipo9.L antibody, cnrP antibody, Ranbp9 antibody, ranbp9.L antibody, RANBP9 antibody, ranbp9 antibody

Background:

Synonyms: RANB9_HUMAN, Ran-binding protein 9, RanBP9, BPM-L, BPM90, Ran-binding protein M, RanBPM, RanBP7.

Background: May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA.

Gene ID: 10048

UniProt: Q96S59

Pathways: Protein targeting to Nucleus