CYP11B2 antibody (AA 221-320)

Catalog No. ABIN7091020

Product Details anti-CYP11B2 Antibody

Target: CYP11B2 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2))

Binding Specificity: AA 221-320

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP11B2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CYP11B2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF()
ICC 1:100-500

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CYP11B2

Target: CYP11B2 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2))

Alternative Name: CYP11B2 (CYP11B2 Products)

Synonyms: ALDOS antibody, CPN2 antibody, CYP11B antibody, CYP11BL antibody, CYPXIB2 antibody, P-450C18 antibody, P450C18 antibody, P450aldo antibody, Cpn2 antibody, Cyp11b antibody, Cyp11b-2 antibody, Cp45as antibody, Cyp11b3 antibody, RNCP45AS antibody, cytochrome P450 family 11 subfamily B member 2 antibody, cytochrome P450, family 11, subfamily b, polypeptide 2 antibody, aldosterone synthase antibody, cytochrome P450, family 11, subfamily B, polypeptide 2 antibody, cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 2 antibody, CYP11B2 antibody, Cyp11b2 antibody

Background:

Synonyms: CYP 11B2, CYP11B2, CYPXI11B2, Cytochrome P450 1111B2, Cytochrome P450 1111B2 mitochondrial, Cytochrome P450 family 11 subfamily B polypeptide 2, Cytochrome P450 subfamily XIB (cholesterol side chain cleavage), Cytochrome P450 subfamily XI11B2, Cytochrome P450C1111B2, C11B2_HUMAN.

Background: Preferentially catalyzes the conversion of 11-deoxycorticosterone to aldosterone via corticosterone and 18-hydroxycorticosterone.

Gene ID: 1585

UniProt: P19099

Pathways: ACE Inhibitor Pathway, Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process, Feeding Behaviour