BRCA2 antibody
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- Target See all BRCA2 Antibodies
- BRCA2 (Breast Cancer 2, Early Onset (BRCA2))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This BRCA2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Predicted Reactivity
- Human
- Immunogen
- Recombinant human BRCA2_HUMAN.
- Clone
- F2H5
- Top Product
- Discover our top product BRCA2 Primary Antibody
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anti-Breast Cancer 2, Early Onset (BRCA2) (AA 21-130) antibody
BRCA2 Reactivity: Human WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
anti-Breast Cancer 2, Early Onset (BRCA2) antibodyBRCA2 Reactivity: Human, Rat WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Breast Cancer 2, Early Onset (BRCA2) (AA 2990-3232) antibodyBRCA2 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Breast Cancer 2, Early Onset (BRCA2) (AA 3319-3418) antibodyBRCA2 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 3D12 unconjugated
anti-Breast Cancer 2, Early Onset (BRCA2) (AA 1-300) antibodyBRCA2 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Breast Cancer 2, Early Onset (BRCA2) (AA 2913-3151) antibodyBRCA2 Reactivity: Rat WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Breast Cancer 2, Early Onset (BRCA2) (AA 2308-2537) antibodyBRCA2 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Breast Cancer 2, Early Onset (BRCA2) (AA 2737-2874) antibodyBRCA2 Reactivity: Zebrafish (Danio rerio) WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Breast Cancer 2, Early Onset (BRCA2) (pSer3291) antibodyBRCA2 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Breast Cancer 2, Early Onset (BRCA2) (AA 251-495) antibodyBRCA2 Reactivity: Human WB Host: Mouse Monoclonal 1643CT739-91-87 unconjugated
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- Application Notes
- WB 1:300-5000
- Restrictions
- For Research Use only
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- Concentration
- 0.5 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- BRCA2 (Breast Cancer 2, Early Onset (BRCA2))
- Alternative Name
- BRCA2 (BRCA2 Products)
- Background
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Synonyms: BRCA 2, BRCA1/BRCA2 containing complex subunit 2, BRCC 2, BRCC2, Breast and ovarian cancer susceptibility gene early onset, Breast cancer 2 early onset, Breast Cancer 2 tumor suppressor, Breast cancer susceptibility protein BRCA2, Breast cancer type 2 susceptibility protein, FACD, FAD 1, FAD, FAD1, FANCB, FANCD 1, FANCD, FANCD1, Fanconi anemia complementation group D1, Fanconi anemia group D1 protein, OTTHUMP00000018803, OTTHUMP00000042401, BRCA2_HUMAN.
Background: Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing RAD51-ssDNA filaments by blocking ATP hydrolysis. May participate in S phase checkpoint activation. Binds selectively to ssDNA, and to ssDNA in tailed duplexes and replication fork structures. In concert with NPM1, regulates centrosome duplication.
- Gene ID
- 675
- UniProt
- P51587
- Pathways
- DNA Damage Repair, M Phase, Maintenance of Protein Location
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