ABCB4 antibody

Catalog No. ABIN7090763

Product Details anti-ABCB4 Antibody

Target: ABCB4 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ABCB4 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: Human

Purification: Purified by Protein G.

Immunogen: Recombinant human ABCB4.

Clone: Y5T3

Isotype: IgG1 kappa

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ABCB4

Target: ABCB4 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4))

Alternative Name: ABCB4 (ABCB4 Products)

Background:

Synonyms: ABC 21, ABC B4, ABC21, ABCB 4, ATP binding cassette sub family B MDR/TAP member 4, ATP binding cassette sub family B member 4, ATP-binding cassette sub-family B member 4, MDR 3, MDR2, MDR2/3, MDR3, MDR3 P glycoprotein, MDR3 P gp, MDR3_HUMAN, Multidrug resistance protein 3, Multiple drug resistance 3, P glycoprotein 3, P-glycoprotein 3, PFIC 3, PFIC3, PGY 3, PGY3.

Background: Mediates ATP-dependent export of organic anions and drugs from the cytoplasm. Hydrolyzes ATP with low efficiency. Human MDR3 is not capable of conferring drug resistance. Mediates the translocation of phosphatidylcholine across the canalicular membrane of the hepatocyte.

Gene ID: 5244

UniProt: P21439

Pathways: Regulation of Lipid Metabolism by PPARalpha