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TXN2 antibody (AA 101-166) (Biotin)

TXN2 Reactivity: Rat WB, ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN705973
  • Target See all TXN2 Antibodies
    TXN2 (Thioredoxin 2 (TXN2))
    Binding Specificity
    • 14
    • 9
    • 8
    • 6
    • 3
    • 1
    AA 101-166
    Reactivity
    • 37
    • 28
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Rat
    Host
    • 51
    • 1
    Rabbit
    Clonality
    • 50
    • 2
    Polyclonal
    Conjugate
    • 19
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TXN2 antibody is conjugated to Biotin
    Application
    • 38
    • 14
    • 13
    • 13
    • 12
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Rat
    Predicted Reactivity
    Human,Mouse,Dog,Cow,Pig,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Thioredoxin 2
    Isotype
    IgG
    Top Product
    Discover our top product TXN2 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    TXN2 (Thioredoxin 2 (TXN2))
    Alternative Name
    Thioredoxin 2 (TXN2 Products)
    Synonyms
    MT-TRX antibody, MTRX antibody, TRX2 antibody, 31884 antibody, CG31884 antibody, CG3864 antibody, DTrx-2 antibody, DmTrx-2 antibody, DmelTrx-2 antibody, Dmel\\CG31884 antibody, Trx antibody, anon-WO0118547.188 antibody, dmtrx-2 antibody, 2510006J11Rik antibody, AI788873 antibody, Trx2 antibody, zgc:77127 antibody, thioredoxin 2 antibody, thioredoxin-2 antibody, thiol reductase thioredoxin antibody, thioredoxin 2 L homeolog antibody, TXN2 antibody, Trx-2 antibody, LOC409451 antibody, VPA0972 antibody, VS_RS18125 antibody, VCD_000568 antibody, VEA_000083 antibody, trx2 antibody, Txn2 antibody, txn2 antibody, txn2.L antibody
    Background

    Synonyms: mitochondrial thioredoxin, MT-TRX, MTRX, thioredoxin 2 precursor, Thioredoxin mitochondrial, Thioredoxin2, TRX 2, TRX2, TXN 2, TXN2.

    Background: Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells. Trx contains a redox-active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds. Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor. The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations. Specific protein disulfide targets for reduction by Trx include protein disulfide isomerase(PDI) and a number of transcription factors such as p53, NF-kB and AP-1. Trx is also capable of removing H2O2, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins.

    Gene ID
    25828
    Pathways
    Cell RedoxHomeostasis
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