TBL1XR1 antibody (AA 231-330)

Catalog No. ABIN705431

Product Details anti-TBL1XR1 Antibody

Target: TBL1XR1 (Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1))

Binding Specificity: AA 231-330

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBL1XR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TBLR1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TBL1XR1

Target: TBL1XR1 (Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1))

Alternative Name: TBLR1 (TBL1XR1 Products)

Synonyms: tbl1xr1 antibody, zgc:63617 antibody, c21 antibody, dc42 antibody, ira1 antibody, TBLR1 antibody, TBL1XR1 antibody, wu:fc46g07 antibody, zgc:110312 antibody, C21 antibody, DC42 antibody, IRA1 antibody, RGD1560053 antibody, 8030499H02Rik antibody, A630076E03Rik antibody, AW539987 antibody, C230089I12Rik antibody, Ira1 antibody, transducin (beta)-like 1 X-linked receptor 1b antibody, transducin (beta)-like 1 X-linked receptor 1 antibody, transducin (beta)-like 1 X-linked receptor 1a antibody, transducin beta like 1 X-linked receptor 1 antibody, transducin (beta)-like 1X-linked receptor 1 antibody, tbl1xr1b antibody, tbl1xr1 antibody, tbl1xr1a antibody, TBL1XR1 antibody, Tbl1xr1 antibody

Background:

Synonyms: C21, DC42, IRA1, TBLR1, F-box-like/WD repeat-containing protein TBL1XR1, Nuclear receptor corepressor/HDAC3 complex subunit TBLR1, TBL1-related protein 1, Transducin beta-like 1X-related protein 1, TBL1XR1

Background: F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation.

Gene ID: 79718

UniProt: Q9BZK7

Pathways: Regulation of Lipid Metabolism by PPARalpha