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MHC Class II HLA-DP/DQ/DR antibody (FITC)

GMP Grade HLA-DP/DQ/DR Reactivity: Human FACS Host: Mouse Monoclonal IVA12 FITC
Catalog No. ABIN7077534
  • Target See all MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR) products
    MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR)
    Reactivity
    • 18
    • 1
    Human
    Host
    • 16
    • 2
    Mouse
    Clonality
    • 18
    Monoclonal
    Conjugate
    • 11
    • 3
    • 2
    • 2
    This MHC Class II HLA-DP/DQ/DR antibody is conjugated to FITC
    Application
    • 16
    • 8
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Purpose
    Anti-HLA-DR, DP, DQ FITC Antibody
    Characteristics
    The clone IVA12 recognizes the shared epitopes of human leukocyte antigen (HLA) class II molecules HLA-DP, HLA-DQ and HLA-DR heterodimeric cell surface glycoproteins comprised of an α (heavy) chain and a β (light) chain. They are expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional antigen presenting cells (APCs). HLA-Class II expressing APCs specifically present antigens recognized by TCR/CD3 complex of CD4+ T cells. Reactive microglia and perivascular cells in multiple sclerosis lesions express all three types of HLA-Class II molecules, whereas microglia in the normal CNS express HLA-DR only.
    Purification
    Purified
    Purity
    >95 %
    Grade
    GMP Grade
    Immunogen
    Priess human B cell line
    Clone
    IVA12
    Isotype
    IgG1, kappa
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    2-8°C, Conjugated antibodies should never be frozen.
  • Target
    MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR)
    Alternative Name
    HLA-DR, DP, DQ (HLA-DP/DQ/DR Products)
    Pathways
    Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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