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EpCAM antibody (Biotin)
GMP Grade
EPCAM
Reactivity: Human
FACS
Host: Mouse
Monoclonal
HEA-125
Biotin
Product Details anti-EpCAM Antibody (Biotin)
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Target
See all EpCAM (EPCAM) Antibodies
EpCAM (EPCAM)
(Epithelial Cell Adhesion Molecule (EPCAM))
Reactivity
All reactivities for EpCAM antibodies
Human
Host
All hosts for EpCAM antibodies
Mouse
Clonality
All clonalities for EpCAM antibodies
Monoclonal
Conjugate
All conjugates for EpCAM antibodies
This EpCAM antibody is conjugated to Biotin
Application
All applications for EpCAM antibodies
Flow Cytometry (FACS)
Purpose
CD326 Biotin Antibody
Characteristics
The clone HEA-125 recognizes epithelium-specific surface glycoprotein having ~34 kDa which is currently known as EpCAM (Epithelial Cell Adhesion Molecule) or CD326. This antigen is expressed on most normal epithelial cells and highly expressed gastrointestinal carcinomas. It functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.
Purification
Purified
Purity
>95 %
Grade
GMP Grade
Immunogen
Human colon carcinoma cell line HT-29
Clone
HEA-125
Isotype
IgG1, kappa
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS pH 7.2, 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
2-8°C, Conjugated antibodies should never be frozen.
Target Details for EpCAM
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Target
EpCAM (EPCAM)
(Epithelial Cell Adhesion Molecule (EPCAM))
Alternative Name
CD326 (EPCAM Products )
Gene ID
4072
UniProt
P16422
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