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CD276 antibody (Biotin)

Name: CD276 antibody (Biotin)
SKU: ABIN7077083
Price: 261.82 USD
Availability: InStock

GMP Grade CD276 Reactivity: Human FACS Host: Mouse Monoclonal DCN-70 Biotin

FACS

1 image

Catalog No. ABIN7077083

Datasheet as PDF

Target See all CD276 Antibodies

CD276
Reactivity
61

34

9

5

5

3

2

2

1
Human
Host
47

15

7

1
Mouse
Compatible Secondaries
Clonality
43

26

1
Monoclonal
Conjugate
37

5

5

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD276 antibody is conjugated to Biotin
Application
45

23

19

14

13

9

8

7

7

4

3

3

2
Flow Cytometry (FACS)

Purpose

CD276 Biotin Antibody

Characteristics

The clone DCN.70, a mouse monoclonal antibody selectively binds with a k type I membrane protein commonly known as CD276, a member of B7-H3 immunoregulatory family. It is not expressed by lymphocytes or granulocytes but weakly expressed on resting monocytes. Increased expression is observed on monocytes derived dendritic cells as well as in a variety of cancer types, including breast, pancreatic, and ovarian cancer. CD276 expression has been correlated with poor survival in ovarian cancer subjects. CD276 blockade, especially when combined with an anti-PD-1 blockade, is a promising strategy for the treatment of B7-H3-expressing NSCLCs that arerefractory to anti-PD-1 therapy, making CD276 a promising clinical molecular target.

Purification

Purified

Purity

>95 %

Grade

GMP Grade

Immunogen

Human Dendritic Cells

Clone

DCN-70

Isotype

IgG1, kappa

Top Product

Discover our top product CD276 Primary Antibody
anti-CD276 (CD276) (AA 29-466) antibody
CD276 Reactivity: Human ELISA, FACS, IHC, ICC Host: Mouse Monoclonal 8C1C2 unconjugated

anti-CD276 (CD276) (AA 47-219) antibody
CD276 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-CD276 (CD276) (AA 493-522), (C-Term) antibody
CD276 Reactivity: Human WB, FACS, IHC (p), IF Host: Rabbit Polyclonal RB31111 unconjugated

anti-CD276 (CD276) (AA 47-213) antibody
CD276 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-CD276 (CD276) antibody
CD276 Reactivity: Human ELISA, FACS, IHC Host: Mouse Monoclonal 6A1 unconjugated

anti-CD276 (CD276) (AA 237-358) antibody
CD276 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 4E12 unconjugated

anti-CD276 (CD276) (AA 100-200) antibody
CD276 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-CD276 (CD276) (AA 47-219) antibody
CD276 Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal C2 unconjugated

anti-CD276 (CD276) (AA 29-200) antibody
CD276 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated

anti-CD276 (CD276) (AA 101-200) antibody
CD276 Reactivity: Human, Mouse WB, ELISA, ICC, IHC (p), IF (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Format

Liquid

Buffer

PBS pH 7.2, 0.09 % sodium azide

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C

Storage Comment

2-8°C, Conjugated antibodies should never be frozen.
Target

CD276

Alternative Name

CD276 (CD276 Products)

Synonyms

sc:d0645 antibody, zgc:158279 antibody, 6030411F23Rik antibody, AU016588 antibody, B7RP-2 antibody, B7h3 antibody, B7H3 antibody, 4Ig-B7-H3 antibody, B7-H3 antibody, CD276 molecule antibody, CD276 molecule S homeolog antibody, CD276 antigen antibody, Cd276 molecule antibody, CD276 antibody, cd276.S antibody, cd276 antibody, Cd276 antibody

Gene ID

80381

UniProt

Q5ZPR3

Pathways

Cancer Immune Checkpoints