CCR2 antibody (FITC)

Catalog No. ABIN7076994

Product Details anti-CCR2 Antibody (FITC)

Target: CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CCR2 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Purpose: CD192 FITC Antibody

Characteristics: The clone 1D9, a mouse monoclonal antibody selectively recognizes C-C chemokine receptor type 2 (CCR2), a cell surface protein known as CD192. It belongs to the beta chemokine receptor family having seven transmembrane (7-TM) G protein-linked receptors. CD192 interacts with its ligands CCL2, CCL8 and CCL16. It is expressed on basophils, monocytes/macrophages, dendritic cells, activated T cells and B cells. CD192 plays an important role in the monocytic infiltration of tissues associated with diseases including atherosclerosis, rheumatoid arthritis, and tumors.

Purification: Purified

Purity: >95 %

Grade: GMP Grade

Immunogen: CCR2 transfected human cell line

Clone: 1D9

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C, Conjugated antibodies should never be frozen.

Target Details for CCR2

Target: CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

Alternative Name: CD192 (CCR2 Products)

Gene ID: 729230

UniProt: P41597

Pathways: cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process