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CD4 antibody (FITC)

Name: CD4 antibody (FITC)
SKU: ABIN7076564
Price: 312.73 USD
Availability: InStock

GMP Grade CD4 Reactivity: Human, Rhesus Monkey, Cynomolgus FACS Host: Mouse Monoclonal SK3 FITC

FACS

1 image

Catalog No. ABIN7076564

Datasheet as PDF

Target See all CD4 Antibodies

CD4
Reactivity
323

200

115

48

24

19

19

17

17

10

10

10

10

10

10

9

9

9

8

5

4

2

1

1

1

1

1
Human, Rhesus Monkey, Cynomolgus
Host
331

146

110

3

3

1
Mouse
Compatible Secondaries
Clonality
449

137

5
Monoclonal
Conjugate
201

69

62

44

36

12

11

10

10

9

8

8

5

5

4

4

4

4

4

4

4

4

4

4

4

4

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1
This CD4 antibody is conjugated to FITC
Application
473

190

125

102

92

71

69

42

39

34

31

28

10

8

8

7

6

6

5

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1
Flow Cytometry (FACS)

Purpose

CD4 FITC Antibody

Characteristics

The clone SK3, a mouse monoclonal antibody selectively binds with a 55-59kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. CD4 contains four extracellular Ig-like domains (D1-D4). The epitope for SK3 is located within the D3 domain of the protein, which has a structure resembling an Ig variable domain. Expression of CD4 is observed in subsets of T lymphocytes, monocytes, macrophages, and dendritic cells. Through interaction of MHC-II, CD4 facilitates cell-cell interaction, thymic differentiation, and activation of downstream signaling cascades. HIV infection of T-cells is instigated through binding of HIV to CD4. Binding of SK3 antibody blocks HIV infection through CD4 and also blocks the mixed lymphocyte reaction (MLR).

Purification

Purified

Purity

>95 %

Grade

GMP Grade

Immunogen

Human peripheral blood T cell

Clone

SK3

Isotype

IgG1, kappa

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CD4 Reactivity: Human, Mouse, Rat, Chicken, Monkey, Dog, Pig, Cat, Cow, Rabbit, Sheep, Guinea Pig, Goat, Horse, Avian, Donkey, Hamster WB Host: Goat Polyclonal unconjugated

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CD4 Reactivity: Human, Mouse, Rat FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated

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CD4 Reactivity: Human FACS, WB, CyTOF Host: Mouse Monoclonal MEM-241 unconjugated

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CD4 Reactivity: Mouse FACS, IP, IHC (fro), ICC, Func Host: Rat Monoclonal GK1-5 unconjugated

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CD4 Reactivity: Human, Mouse, Rat FACS, WB, IHC (p) Host: Rabbit Polyclonal unconjugated

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CD4 Reactivity: Human FACS Host: Mouse Monoclonal MEM-241 FITC

anti-CD4 (CD4) (N-Term) antibody (PE)
CD4 Reactivity: Human FACS Host: Mouse Monoclonal MEM-241 PE

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CD4 Reactivity: Rat FACS Host: Mouse Monoclonal OX-35 PE

anti-CD4 (CD4) (AA 26-200) antibody
CD4 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated

Application Notes

FC: 5 µL/test We recommend that every lab carries out an initial titration study before running your samples to ensure that the optimal concentration is selected for your application.

Restrictions

For Research Use only
Format

Liquid

Buffer

PBS, pH 7.2, 0.09 % Sodium azide and 0.2 % (w/v) BSA

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C

Storage Comment

2-8°C, Conjugated antibodies should never be frozen.
Target

CD4

Alternative Name

CD4 (CD4 Products)

Gene ID

920

NCBI Accession

NM_000616

UniProt

P01730

Pathways

TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events