ZFPM2 antibody

Catalog No. ABIN7076277

Product Details anti-ZFPM2 Antibody

Target: ZFPM2 (Zinc Finger Protein, FOG Family Member 2 (ZFPM2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZFPM2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse FOG2

Application Details

Application Notes: WB (M,R) 1:1000-1:2000, IHC/IF (M,R) 1:1800-1:3600/1:300-1:600

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for ZFPM2

Target: ZFPM2 (Zinc Finger Protein, FOG Family Member 2 (ZFPM2))

Alternative Name: FOG2 (ZFPM2 Products)

Synonyms: B330005D23Rik antibody, FOG-2 antibody, FOG2 antibody, DIH3 antibody, ZC2HC11B antibody, ZNF89B antibody, hFOG-2 antibody, FOG-A antibody, fog2a antibody, zgc:152696 antibody, zinc finger protein, multitype 2 antibody, zinc finger protein, FOG family member 2 antibody, zinc finger protein, FOG family member 2a antibody, Zfpm2 antibody, ZFPM2 antibody, zfpm2a antibody

Background: FOG-2 is the transcriptional cofactors of FOG family . FOG-2 is able to both positively and negatively influence GATA mediated transcription. FOG-2 is predominantly expressed in heart, neurons and gonads, and it preferentially participates in the regulation of GATA-3, GATA-4 and GATA-6. In cardiomyocytes and fibroblasts, FOG-2 inhibits GATA-4 transcriptional activity, yet FOG-2 restores GATA-1 mediated transcription in erythroid cultures deficient in FOG, suggesting that the observed effects of FOG-2 are context specific and vary between cellular systems.

Molecular Weight: 128 kDa

Gene ID: 22762

NCBI Accession: NP_035896

UniProt: Q8CCH7