WDR59 antibody
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- Target See all WDR59 products
- WDR59 (WD Repeat Domain 59 (WDR59))
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Reactivity
- Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This WDR59 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Rat
- Purification
- Affinity purification
- Immunogen
- Recombinant protein corresponding to Mouse WDR59
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- Application Notes
- WB (M,R) 1: 500-1: 1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- WDR59 (WD Repeat Domain 59 (WDR59))
- Alternative Name
- WDR59 (WDR59 Products)
- Synonyms
- 5430401O09Rik antibody, Cdw12 antibody, WD repeat domain 59 antibody, WDR59 antibody, Wdr59 antibody
- Background
- As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex. It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1.
- Molecular Weight
- 112 kDa
- Gene ID
- 319481
- NCBI Accession
- NP_001164213
- UniProt
- Q8C0M0
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