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UBR5 antibody
UBR5
Reactivity: Mouse, Rat
IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-UBR5 Antibody
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Target
See all UBR5 Antibodies
UBR5
(Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5))
Reactivity
All reactivities for UBR5 antibodies
Mouse, Rat
Host
All hosts for UBR5 antibodies
Rabbit
Clonality
All clonalities for UBR5 antibodies
Polyclonal
Conjugate
All conjugates for UBR5 antibodies
This UBR5 antibody is un-conjugated
Application
All applications for UBR5 antibodies
Immunohistochemistry (IHC), Immunofluorescence (IF)
Cross-Reactivity
Rat
Purification
Affinity purification
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse EDD
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Discover our top product UBR5 Primary Antibody
Alternatives
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Application Details
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Application Notes
IHC/IF (M,R) 1:350-1:700
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS, pH 7.4, 0.02 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Target Details for UBR5
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Target
UBR5
(Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5))
Alternative Name
EDD (UBR5 Products )
Synonyms
DD5 antibody, EDD antibody, EDD1 antibody, HYD antibody, 4432411E13Rik antibody, AW549941 antibody, C77315 antibody, D030042K14 antibody, Edd antibody, Edd1 antibody, mKIAA0896 antibody, Dd5 antibody, Rat100 antibody, ubiquitin protein ligase E3 component n-recognin 5 antibody, UBR5 antibody, Ubr5 antibody
Background
UBR5, also named as ubiquitin protein ligase E3 component n-reconin5, is a HECT domain-containing protein as a myocardin-binding protein. UBR5 is highly conserved in metazoans, has unique structural features, and has been implicated in regulation of DNA damage response, metabolism, transcription, and apoptosis. Hence, UBR5 is a key regulator of cell signaling relevant to broad areas of cancer biology . The human UBR5 gene has 59 exons, encoding an approximately 10kb mRNA and >300 kDa protein with widespread expression in various cell types.
Gene ID
70790
NCBI Accession
NP_001074828
UniProt
Q80TP3
Pathways
Intracellular Steroid Hormone Receptor Signaling Pathway
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