TWF2 antibody

Catalog No. ABIN7076085

Product Details anti-TWF2 Antibody

Target: TWF2 (Twinfilin, Actin-Binding Protein, Homolog 2 (Drosophila) (TWF2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TWF2 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse TWF2

Application Details

Application Notes: WB (H,M,R) 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for TWF2

Target: TWF2 (Twinfilin, Actin-Binding Protein, Homolog 2 (Drosophila) (TWF2))

Alternative Name: TWF2 (TWF2 Products)

Background: TWF2 (Twinfilin 2) was identified by its interaction with the catalytic domain of protein kinase C zeta. It contains an actin binding site and an ATP binding site and is most closely related to twinfilin (PTK9), a conserved actin monomer binding protein. TWF2 is an actin binding protein involved in motile and morphological processes. It inhibits actin polymerization, likely by sequestering G actin. By capping the barbed ends of filaments, it also regulates motility. It seems to play an important role in clathrin mediated endocytosis and distribution of endocytic organelles.

Molecular Weight: 39 kDa

Gene ID: 23999

UniProt: Q9Z0P5

Pathways: Regulation of Actin Filament Polymerization, Regulation of Cell Size, Maintenance of Protein Location, Toll-Like Receptors Cascades