TTL antibody

Catalog No. ABIN7076048

Product Details anti-TTL Antibody

Target: TTL (Tubulin tyrosine Ligase (TTL))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTL antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse TTL

Application Details

Application Notes: IHC/IF (M,R) 1:2000-1:4000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for TTL

Target: TTL (Tubulin tyrosine Ligase (TTL))

Alternative Name: TTL (TTL Products)

Synonyms: 2410003M22Rik antibody, 2700049H19Rik antibody, AI848570 antibody, wu:fb93a09 antibody, zgc:153332 antibody, tubulin tyrosine ligase antibody, Ttl antibody, TTL antibody, ttl antibody

Background: Tubulin-tyrosine ligase (TTL) is the enzyme responsible for the reversible addition of a tyrosine residue at the carboxyl end of alpha-tubulin. TTL forms stable complexes with tubulin and inhibit tubulin polymerization. TTL is frequently suppressed during tumor progression with resulting accumulation of detyrosinated alpha-tubulin in tumor cells. TTL suppression in human cancers is associated with increased tumor aggressiveness.

Gene ID: 69737

NCBI Accession: NP_081468

UniProt: P38585

Pathways: Regulation of Cell Size