Tbca13 antibody, CFA antibody, tbca antibody, zgc:56262 antibody, tubulin cofactor A antibody, tubulin folding cofactor A antibody, tubulin folding cofactor A S homeolog antibody, tubulin cofactor a antibody, Tbca antibody, TBCA antibody, tbca.S antibody, tbca antibody
Background
The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex, interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. This gene encodes chaperonin cofactor A. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.