TRIM26 antibody

Catalog No. ABIN7076014

Product Details anti-TRIM26 Antibody

Target: TRIM26 (Tripartite Motif Containing 26 (TRIM26))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM26 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse TRIM26

Application Details

Application Notes: WB (H,M,R) 1:1000-1:1500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for TRIM26

Target: TRIM26 (Tripartite Motif Containing 26 (TRIM26))

Alternative Name: TRIM26 (TRIM26 Products)

Background: TRIM26 is a member of the tripartite motif (TRIM) protein family composed of more than 70 members in human. TRIM proteins share a similar characteristic structure, which includes a RING (R) domain, one or two B-boxes (B), and a coiled coil (CC) domain in the N-terminal and a domain in the C-terminal with variable structures. TRIM26 potentiates virus-triggered IRF3, NF-κB activation, IFN-β induction, and cellular antiviral responses. Further investigation suggests that TRIM26 plays an important role in the antiviral innate immune response by bridging TBK1 to NEMO and mediating TBK1 activation.

Molecular Weight: 63 kDa

Gene ID: 22670

NCBI Accession: NP_001020770

UniProt: Q99PN3