87D3T antibody, CG9364 antibody, Dmel\\CG9364 antibody, ESTS:87D3T antibody, TRE antibody, TREH antibody, Tre antibody, anon-EST:Posey159 antibody, anon-sts38 antibody, GB16316 antibody, TREA antibody, 2210412M19Rik antibody, Trehalase antibody, trehalase antibody, trehalase (brush-border membrane glycoprotein) antibody, Treh antibody, LOC693027 antibody, LOC410795 antibody, TREH antibody
Background
Trehalase, also known as TREH, TREA or α,α-trehalose glucohydrolase, is a 583 amino acid protein belonging to the glycosyl hydrolase 37 family. Localizing to cell membrane and lipid-anchor, Trehalase is expressed in kidney, liver, and small intestine. Trehalase hydrolyses ingested trehalose, a disaccharide formed by two glucose molecules found mainly in insects, fungi, and plants, into cellular substrate glucose. Isolated trehalose intolerance due to deficiencies of Trehalase can result in gastrointestinal symptoms.