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TLE1 antibody
TLE1
Reactivity: Mouse, Rat
IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TLE1 Antibody
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Target
See all TLE1 Antibodies
TLE1
(Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))
Reactivity
All reactivities for TLE1 antibodies
Mouse, Rat
Host
All hosts for TLE1 antibodies
Rabbit
Clonality
All clonalities for TLE1 antibodies
Polyclonal
Conjugate
All conjugates for TLE1 antibodies
This TLE1 antibody is un-conjugated
Application
All applications for TLE1 antibodies
Immunohistochemistry (IHC), Immunofluorescence (IF)
Cross-Reactivity
Rat
Purification
Affinity purification
Immunogen
Recombinant protein corresponding to Mouse TLE 1
Alternatives
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Application Details
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Application Notes
IHC/IF (M,R) 1:1000-1:4000/1:500-1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS, pH 7.4, 0.02 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Target Details for TLE1
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Target
TLE1
(Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))
Alternative Name
TLE 1 (TLE1 Products )
Synonyms
ESG antibody, ESG1 antibody, GRG1 antibody, C230057C06Rik antibody, Estm14 antibody, Grg1 antibody, Tle4l antibody, TLE1 antibody, transducin like enhancer of split 1 antibody, transducin-like enhancer protein 1 antibody, transducin-like enhancer of split 1 antibody, transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) antibody, TLE1 antibody, Smp_150080 antibody, Tle1 antibody, LOC100354911 antibody, LOC100524475 antibody, LOC100061341 antibody
Background
Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
Gene ID
21885
NCBI Accession
NP_001272459
UniProt
Q62440
Pathways
WNT Signaling , SARS-CoV-2 Protein Interactome
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