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Topoisomerase II alpha antibody
TOP2A
Reactivity: Mouse, Rat
IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Topoisomerase II alpha Antibody
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Target
See all Topoisomerase II alpha (TOP2A) Antibodies
Topoisomerase II alpha (TOP2A)
(Topoisomerase (DNA) II alpha 170kDa (TOP2A))
Reactivity
All reactivities for Topoisomerase II alpha antibodies
Mouse, Rat
Host
All hosts for Topoisomerase II alpha antibodies
Rabbit
Clonality
All clonalities for Topoisomerase II alpha antibodies
Polyclonal
Conjugate
All conjugates for Topoisomerase II alpha antibodies
This Topoisomerase II alpha antibody is un-conjugated
Application
All applications for Topoisomerase II alpha antibodies
Immunohistochemistry (IHC), Immunofluorescence (IF)
Cross-Reactivity
Rat
Purification
Affinity purification
Immunogen
Recombinant protein corresponding to Mouse Top2a
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Alternatives
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Application Details
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Application Notes
IHC/IF (M,R) 1:600-1:2000/1:500-1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS, pH 7.4, 0.02 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Target Details for Topoisomerase II alpha
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Target
Topoisomerase II alpha (TOP2A)
(Topoisomerase (DNA) II alpha 170kDa (TOP2A))
Alternative Name
Topoisomerase II alpha (TOP2A Products )
Background
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event.
Gene ID
21973
NCBI Accession
NP_035753
UniProt
Q01320
Pathways
Cell Division Cycle , Mitotic G1-G1/S Phases
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