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Topoisomerase II alpha antibody

TOP2A Reactivity: Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7075937
  • Target See all Topoisomerase II alpha (TOP2A) Antibodies
    Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))
    Reactivity
    • 148
    • 60
    • 30
    • 5
    • 5
    • 3
    • 3
    • 3
    • 1
    Mouse, Rat
    Host
    • 110
    • 38
    Rabbit
    Clonality
    • 99
    • 49
    Polyclonal
    Conjugate
    • 73
    • 11
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Topoisomerase II alpha antibody is un-conjugated
    Application
    • 99
    • 58
    • 54
    • 47
    • 23
    • 18
    • 13
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Rat
    Purification
    Affinity purification
    Immunogen
    Recombinant protein corresponding to Mouse Top2a
    Top Product
    Discover our top product TOP2A Primary Antibody
  • Application Notes
    IHC/IF (M,R) 1:600-1:2000/1:500-1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))
    Alternative Name
    Topoisomerase II alpha (TOP2A Products)
    Synonyms
    TOP2 antibody, TP2A antibody, TOP2A antibody, Top-2 antibody, TOP-2 antibody, F12B17.110 antibody, F12B17_110 antibody, thimet metalloendopeptidase 2 antibody, fc08c07 antibody, wu:fc08c07 antibody, DNA topoisomerase II alpha antibody, DNA topoisomerase II, alpha isozyme antibody, topoisomerase (DNA) II alpha antibody, Zincin-like metalloproteases family protein antibody, TOP2A antibody, Bm1_08705 antibody, Top2a antibody, AT5G10540 antibody, top2a antibody
    Background
    This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event.
    Gene ID
    21973
    NCBI Accession
    NP_035753
    UniProt
    Q01320
    Pathways
    Cell Division Cycle, Mitotic G1-G1/S Phases
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