TGDS antibody

Catalog No. ABIN7075850

Product Details anti-TGDS Antibody

Target: TGDS (TDP-Glucose 4,6-Dehydratase (TGDS))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TGDS antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse TGDS

Application Details

Application Notes: IHC/IF (M,R) 1:3000-1:6000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for TGDS

Target: TGDS (TDP-Glucose 4,6-Dehydratase (TGDS))

Alternative Name: TGDS (TGDS Products)

Synonyms: SDR2E1 antibody, TDPGD antibody, 2610017J16Rik antibody, 2610025M23Rik antibody, AI648925 antibody, TDP-glucose 4,6-dehydratase antibody, TGDS antibody, Tgds antibody

Background: The protein encoded by this gene is a member of the short-chain dehydrogenases/reductases (SDR) superfamily, and is thought to contain a nicotinamide adenine dinucleotide (NAD) binding domain. This large SDR family of enzymes is involved in the metabolism of a variety of compounds, including prostaglandins, retinoids, lipids, steroid hormones, and xenobiotics. Mutations in this gene have been associated with Catel-Manzke syndrome, which is characterized by Pierre Robin sequence, and radial deviation of the index finger due to the presence of an accessory bone between the index finger and its proximal phalanx. Pierre Robin sequence is defined by an undersized jaw, backwards displacement of the tongue base that causes an obstruction of the airways, and can also be associated with a cleft palate.

Gene ID: 76355

NCBI Accession: NP_083854

UniProt: Q8VDR7