TBC1D17 antibody
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- Target See all TBC1D17 Antibodies
- TBC1D17 (TBC1 Domain Family, Member 17 (TBC1D17))
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Reactivity
- Human, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TBC1D17 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Human, Rat
- Purification
- Affinity purification
- Immunogen
- Recombinant protein corresponding to Mouse TBC1D17
- Top Product
- Discover our top product TBC1D17 Primary Antibody
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- Application Notes
- WB (H,R) 1:500-1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- TBC1D17 (TBC1 Domain Family, Member 17 (TBC1D17))
- Alternative Name
- TBC1D17 (TBC1D17 Products)
- Synonyms
- BC017607 antibody, TBC1 domain family member 17 antibody, TBC1 domain family, member 17 antibody, TBC1D17 antibody, Tbc1d17 antibody
- Background
- Probable GTPase-activating protein for Rab8, its transient association with Rab8 is mediated by OPTN. Inhibits Rab8-mediated endocytic trafficking, such as of transferrin receptor (TfR) and reduces Rab8 recruitnment to tubules emanating from the endocytic recycling compartment (ERC). Involved in regulation of autophagy. Mediates inhibition of autophagy caused by the OPTN variant GLC1E LYS-50, the function requires its catalytic activity, however, the involved Rab is not known.
- Molecular Weight
- 73 kDa
- Gene ID
- 233204
- NCBI Accession
- NP_001036120
- UniProt
- Q8BYH7
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