SIN3A antibody
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- Target See all SIN3A Antibodies
- SIN3A (SIN3 homolog A, transcription regulator (SIN3A))
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Reactivity
- Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SIN3A antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Rat
- Purification
- Affinity purification
- Immunogen
- Recombinant protein corresponding to Mouse mSin3A
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- Application Notes
- IHC/IF (M,R) 1:100-1:200/1:100-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- SIN3A (SIN3 homolog A, transcription regulator (SIN3A))
- Alternative Name
- mSin3A (SIN3A Products)
- Synonyms
- AW553200 antibody, Sin3 antibody, mKIAA4126 antibody, mSin3A antibody, zgc:162128 antibody, SIN3A antibody, SIN3 transcription regulator family member A antibody, transcriptional regulator, SIN3A (yeast) antibody, paired amphipathic helix protein Sin3a antibody, SIN3 transcription regulator family member Aa antibody, SIN3A antibody, Sin3a antibody, LOC100641919 antibody, sin3aa antibody, LOC100439524 antibody
- Background
- The protein encoded by this gene is a transcriptional regulatory protein. It contains paired amphipathic helix (PAH) domains, which are important for protein-protein interactions and may mediate repression by the Mad-Max complex. And It acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation.
- Gene ID
- 20466
- NCBI Accession
- NP_001103820
- UniProt
- Q60520
- Pathways
- Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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