RBM45 antibody

Catalog No. ABIN7075477

Product Details anti-RBM45 Antibody

Target: RBM45 (RNA Binding Motif Protein 45 (RBM45))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBM45 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (IHC)

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse RB-1

Application Details

Application Notes: IHC/IF (M,R) 1:700-1:1400/1:500-1:2500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for RBM45

Target: RBM45 (RNA Binding Motif Protein 45 (RBM45))

Alternative Name: RB-1 (RBM45 Products)

Background: RB1 belongs to the retinoblastoma protein family. It is a key regulator of entry into cell division that acts as a tumor suppressor. RB1 acts as a transcription repressor of E2F1 target genes. The underphosphorylated, active form of RB1 interacts with E2F1 and represses its transcription activity, leading to cell cycle arrest. It is directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation.

Gene ID: 19645

NCBI Accession: NP_033055

UniProt: P13405