ARHGAP17 antibody

Catalog No. ABIN7075416

Product Details anti-ARHGAP17 Antibody

Target: ARHGAP17 (rho GTPase Activating Protein 17 (ARHGAP17))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGAP17 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse ARHGAP17

Application Details

Application Notes: WB (M) 1:250-1:500, IHC/IF (R) 1:500-1:1500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for ARHGAP17

Target: ARHGAP17 (rho GTPase Activating Protein 17 (ARHGAP17))

Alternative Name: ARHGAP17 (ARHGAP17 Products)

Synonyms: MST066 antibody, MST110 antibody, MSTP038 antibody, MSTP066 antibody, MSTP110 antibody, NADRIN antibody, PP367 antibody, PP4534 antibody, RICH1 antibody, RICH1B antibody, WBP15 antibody, 5730403H17Rik antibody, Nadrin antibody, Nadrin2 antibody, Rich1 antibody, Wbp15 antibody, Rho GTPase activating protein 17 antibody, ARHGAP17 antibody, arhgap17 antibody, Arhgap17 antibody

Background: ARHGAP17 is a Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. It specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. RHGAP17 participates in the Ca(2+)-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1.

Molecular Weight: 81 kDa

Gene ID: 70497

NCBI Accession: NP_001116112

UniProt: Q3UIA2