RMND5A antibody

Catalog No. ABIN7075401

Product Details anti-RMND5A Antibody

Target: RMND5A (Required For Meiotic Nuclear Division 5 Homolog A (RMND5A))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RMND5A antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse RMND5A

Application Details

Application Notes: IHC/IF (M,R) 1:1500-1:3000/1:600-1:1200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for RMND5A

Target: RMND5A (Required For Meiotic Nuclear Division 5 Homolog A (RMND5A))

Alternative Name: RMND5A (RMND5A Products)

Synonyms: CTLH antibody, GID2 antibody, GID2A antibody, RMD5 antibody, p44CTLH antibody, 1110007A06Rik antibody, AJ237586 antibody, AW125795 antibody, Gid2 antibody, MTA.D02.090 antibody, required for meiotic nuclear division 5 homolog A antibody, RMND5A antibody, Rmnd5a antibody

Background: Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. Catalytic activity of the complex is required for normal cell proliferation. The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1.

Gene ID: 68477

NCBI Accession: NP_077250

UniProt: Q80YQ8