PPP2R2D antibody

Catalog No. ABIN7075277

Product Details anti-PPP2R2D Antibody

Target: PPP2R2D (Protein Phosphatase 2, Regulatory Subunit B, delta (PPP2R2D))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2R2D antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse PPP2R2D

Application Details

Application Notes: WB (H,M,R) 1: 1000-1: 2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for PPP2R2D

Target: PPP2R2D (Protein Phosphatase 2, Regulatory Subunit B, delta (PPP2R2D))

Alternative Name: PPP2R2D (PPP2R2D Products)

Synonyms: 1300017E19Rik antibody, D7Ertd753e antibody, MDS026 antibody, protein phosphatase 2, regulatory subunit B, delta antibody, protein phosphatase 2 regulatory subunit Bdelta antibody, protein phosphatase 2 regulatory subunit B, delta S homeolog antibody, Ppp2r2d antibody, PPP2R2D antibody, ppp2r2d.S antibody

Background: B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment .

Molecular Weight: 52 kDa

Gene ID: 52432

NCBI Accession: NP_080667

UniProt: Q925E7