PRR14 antibody
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- Target See all PRR14 Antibodies
- PRR14 (Proline Rich 14 (PRR14))
- Reactivity
- Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PRR14 antibody is un-conjugated
- Application
- Immunofluorescence (IF), Immunohistochemistry (IHC)
- Cross-Reactivity
- Rat
- Purification
- Affinity purification
- Immunogen
- Recombinant protein corresponding to Mouse PRR14
- Top Product
- Discover our top product PRR14 Primary Antibody
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- Application Notes
- IHC/IF (M,R) 1:1600-1:3200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- PRR14 (Proline Rich 14 (PRR14))
- Alternative Name
- PRR14 (PRR14 Products)
- Background
- PRR14 (proline-rich protein 14) is a 585-amino acid protein with a calculated molecular weight of 64 kDa. This protein functions to tether heterochromatin to the nuclear periphery during interphase, through associations with heterochromatin protein 1 (HP1) and the nuclear lamina. After disassembly early in mitosis, PRR14 reassembles in two steps, first binding to anaphase chromosomes through HP1, followed by association with the nuclear lamina in telophase. PRR14 may thereby play a role in specifying HP1-bound heterochromatin for reattachment to the nuclear lamina at mitotic exit.
- Gene ID
- 233895
- UniProt
- Q7TPN9
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