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PNN antibody

PNN Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7075083
  • Target See all PNN Antibodies
    PNN (Pinin, Desmosome Associated Protein (PNN))
    Reactivity
    • 47
    • 24
    • 11
    • 8
    • 7
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 43
    • 4
    Rabbit
    Clonality
    • 44
    • 3
    Polyclonal
    Conjugate
    • 30
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PNN antibody is un-conjugated
    Application
    • 39
    • 25
    • 15
    • 15
    • 6
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human, Rat
    Purification
    Affinity purification
    Immunogen
    KLH conjugated Synthetic peptide corresponding to Mouse PNN/DRSP
  • Application Notes
    IHC/IF (H,M,R) 1:600-1:1200/1:400-1:800
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    PNN (Pinin, Desmosome Associated Protein (PNN))
    Alternative Name
    PNN/DRSP (PNN Products)
    Synonyms
    DRS antibody, DRSP antibody, SDK3 antibody, memA antibody, wu:fb24d03 antibody, pnn antibody, MGC88923 antibody, PNN antibody, AU045199 antibody, D12Ertd512e antibody, CG8383 antibody, Dmel\\CG8383 antibody, dPnn antibody, pinin, desmosome associated protein antibody, pinin antibody, Pinin antibody, PNN antibody, Pnn antibody, pnn antibody, LOC100380709 antibody
    Background
    PNN, also named as DRS or 140 kDa nuclear and cell adhesion-related phosphoprotein, is a 717 amino acid protein, which belongs to the pinin family. PNN localizes in the plasma membrane and is expressed in placenta, lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon, heart, epidermis, esophagus, brain and smooth and skeletal muscle. PNN is expressed strongly in melanoma metastasis lesions and advanced primary tumors. PNN as a transcriptional activator binds to the E-box 1 core sequence of the E-cadherin promoter gene. PNN is involved in the establishment and maintenance of epithelia cell-cell adhesion. PNN is a potential tumor suppressor for renal cell carcinoma.
    Gene ID
    18949
    NCBI Accession
    NP_032917
    UniProt
    O35691
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