CBP20 antibody, CG12357 antibody, Dmel\\CG12357 antibody, 20kDa antibody, 5930413E18Rik antibody, AA536802 antibody, AI843301 antibody, C79367 antibody, CHUNP6917 antibody, zgc:92592 antibody, CBC2 antibody, NIP1 antibody, ATCBP20 antibody, CAP-binding protein 20 antibody, MLN1.12 antibody, MLN1_12 antibody, Ncbp2 antibody, cap binding protein 20 antibody, nuclear cap binding protein subunit 2 antibody, nuclear cap binding protein subunit 2, 20kDa antibody, nuclear cap binding protein subunit 2 L homeolog antibody, nuclear cap-binding protein subunit 2 antibody, CAP-binding protein 20 antibody, Nuclear cap-binding protein subunit 2 antibody, Cbp20 antibody, Ncbp2 antibody, ncbp2 antibody, NCBP2 antibody, ncbp2.L antibody, CBP20 antibody, ncbp-2 antibody
Background
The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein has an RNP domain commonly found in RNA binding proteins, and contains the cap-binding activity. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Multiple transcript variants encoding different isoforms have been found for this gene.