PFAAP5 antibody, N4BP2L2 antibody, DKFZp469E0621 antibody, 92M18.3 antibody, CG005 antibody, 2700092H06Rik antibody, zag1 antibody, NEDD4 binding protein 2 like 2 antibody, NEDD4 binding protein 2-like 2 antibody, NEDD4-binding protein 2-like 2 antibody, N4BP2L2 antibody, LOC100398238 antibody, N4bp2l2 antibody
Background
PFAAP5 is a 583 amino acid nuclear protein that potentially is involved in transcriptional regulation. PFAAP5 is phosphorylated on Ser 199 in response to DNA damage, probably by ATM or ATR. Primarily expressed in bone marrow, PFAAP5 is dramatically down-regulated after exposure to arsenic compounds, an event which precedes neutropenia.