NCK2 antibody

Catalog No. ABIN7074783

Product Details anti-NCK2 Antibody

Target: NCK2 (NCK Adaptor Protein 2 (NCK2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCK2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse Nck-2

Application Details

Application Notes: IHC/IF (H,M,R) 1:1000-1:4000/1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for NCK2

Target: NCK2 (NCK Adaptor Protein 2 (NCK2))

Alternative Name: Nck-2 (NCK2 Products)

Background: Cytoplasmic protein NCK2 (also known as NCK-beta and Grb4) is a protein encoded by the NCK2 gene. NCK belongs to family of adaptor proteins,There are two mammalian NCK genes, NCK1 and NCK2. NCK1 is located in chromosome 3 and NCK2 is located in chromosome 2. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases.

Gene ID: 17974

NCBI Accession: NP_035009

UniProt: O55033

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization