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MYLK3 antibody

MYLK3 Reactivity: Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7074736
  • Target See all MYLK3 Antibodies
    MYLK3 (Myosin Light Chain Kinase 3 (MYLK3))
    Reactivity
    • 50
    • 34
    • 17
    • 1
    • 1
    • 1
    • 1
    Mouse, Rat
    Host
    • 58
    Rabbit
    Clonality
    • 58
    Polyclonal
    Conjugate
    • 18
    • 5
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MYLK3 antibody is un-conjugated
    Application
    • 49
    • 28
    • 24
    • 3
    • 3
    • 2
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Rat
    Purification
    Affinity purification
    Immunogen
    Recombinant protein corresponding to Mouse MYLK3/MLCK
    Top Product
    Discover our top product MYLK3 Primary Antibody
  • Application Notes
    IHC/IF (M,R) 1:600-1:1200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    MYLK3 (Myosin Light Chain Kinase 3 (MYLK3))
    Alternative Name
    MYLK3/MLCK (MYLK3 Products)
    Synonyms
    MLCK antibody, MLCK2 antibody, caMLCK antibody, D830007F02Rik antibody, RGD1305801 antibody, myosin light chain kinase 3 antibody, MYLK3 antibody, Mylk3 antibody
    Background
    The Ca2+/calmodulin-dependent protein kinases (CaM kinases) are a structurally related subfamily of serine/threonine kinases that includes CaMKI, CaMKII, CaMKIV and Myosin light chain kinases (MYLKs, also designated MLCKs). The MYLK kinases phosphorylate Myosin regulatory light chains to catalyze Myosin interaction with Actin filaments, resulting in contractile activity. MYLK3 (Myosin light chain kinase 3) is a 795 amino acid cardiac-specific protein that contains one protein kinase domain and belongs to the protein kinase superfamily. Like other MYLK kinases, MYLK3 is thought to play a role in smooth muscle contraction, specifically using magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of Myosin light chain proteins. Additionally, MYLK3 may regulate sarcomere assembly in heart tissue, possibly mediating proper heart function.
    Gene ID
    213435
    NCBI Accession
    NP_001284541
    UniProt
    Q3UIZ8
    Pathways
    Regulation of Muscle Cell Differentiation
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