MED27 antibody

Catalog No. ABIN7074581

Product Details anti-MED27 Antibody

Target: MED27 (Mediator Complex Subunit 27 (MED27))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED27 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (IHC)

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse MED3

Application Details

Application Notes: IHC/IF (M,R) 1:3600-1:7200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for MED27

Target: MED27 (Mediator Complex Subunit 27 (MED27))

Alternative Name: MED3 (MED27 Products)

Background: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Gene ID: 68975

NCBI Accession: NP_001277419

UniProt: Q9DB40

Pathways: Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha